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Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan

Early detection and accurate monitoring of chronic kidney disease (CKD) could improve care and retard progression to end-stage renal disease. Here, using untargeted metabolomics in 2155 participants including patients with stage 1–5 CKD and healthy controls, we identify five metabolites, including 5...

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Detalles Bibliográficos
Autores principales: Chen, Dan-Qian, Cao, Gang, Chen, Hua, Argyopoulos, Christos P., Yu, Hui, Su, Wei, Chen, Lin, Samuels, David C., Zhuang, Shougang, Bayliss, George P., Zhao, Shilin, Yu, Xiao-Yong, Vaziri, Nosratola D., Wang, Ming, Liu, Dan, Mao, Jia-Rong, Ma, Shi-Xing, Zhao, Jin, Zhang, Yuan, Shang, You-Quan, Kang, Huining, Ye, Fei, Cheng, Xiao-Hong, Li, Xiang-Ri, Zhang, Li, Meng, Mei-Xia, Guo, Yan, Zhao, Ying-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443780/
https://www.ncbi.nlm.nih.gov/pubmed/30931940
http://dx.doi.org/10.1038/s41467-019-09329-0