USP8 maintains embryonic stem cell stemness via deubiquitination of EPG5

Embryonic stem cells (ESCs) can propagate in an undifferentiated state indefinitely in culture and retain the potential to differentiate into any somatic lineage as well as germ cells. The catabolic process autophagy has been reported to be involved in ESC identity regulation, but the underlying mec...

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Detalles Bibliográficos
Autores principales: Gu, Haifeng, Shi, Xingxing, Liu, Chao, Wang, Chaoqun, Sui, Ning, Zhao, Yu, Gong, Jiaqi, Wang, Fuping, Zhang, Hong, Li, Wei, Zhao, Tongbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443784/
https://www.ncbi.nlm.nih.gov/pubmed/30931944
http://dx.doi.org/10.1038/s41467-019-09430-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443784/
https://www.ncbi.nlm.nih.gov/pubmed/30931944
http://dx.doi.org/10.1038/s41467-019-09430-4

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