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USP8 maintains embryonic stem cell stemness via deubiquitination of EPG5
Embryonic stem cells (ESCs) can propagate in an undifferentiated state indefinitely in culture and retain the potential to differentiate into any somatic lineage as well as germ cells. The catabolic process autophagy has been reported to be involved in ESC identity regulation, but the underlying mec...
Autores principales: | Gu, Haifeng, Shi, Xingxing, Liu, Chao, Wang, Chaoqun, Sui, Ning, Zhao, Yu, Gong, Jiaqi, Wang, Fuping, Zhang, Hong, Li, Wei, Zhao, Tongbiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443784/ https://www.ncbi.nlm.nih.gov/pubmed/30931944 http://dx.doi.org/10.1038/s41467-019-09430-4 |
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