A decade of sustained selection pressure on two surface sites of the VP1 protein of Enterovirus A71 suggests that immune evasion may be an indirect driver for virulence

Enterovirus A71 (EV-A71) is an emerging pathogen in the Enterovirus A species group. EV-A71 causes hand, foot and mouth disease (HFMD), with virulent variants exhibiting polio-like acute flaccid paralysis and other central nervous system manifestations. We analysed all enterovirus A71 complete genom...

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Detalles Bibliográficos
Autores principales: Roberts, Ryan, Yee, Pinn Tsin Isabel, Mujawar, Shama, Lahiri, Chandrajit, Poh, Chit Laa, Gatherer, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443798/
https://www.ncbi.nlm.nih.gov/pubmed/30931960
http://dx.doi.org/10.1038/s41598-019-41662-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443798/
https://www.ncbi.nlm.nih.gov/pubmed/30931960
http://dx.doi.org/10.1038/s41598-019-41662-8

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