The protonation state of an evolutionarily conserved histidine modulates domain swapping stability of FoxP1

Forkhead box P (FoxP) proteins are members of the versatile Fox transcription factors, which control the timing and expression of multiple genes for eukaryotic cell homeostasis. Compared to other Fox proteins, they can form domain-swapped dimers through their DNA-binding –forkhead– domains, enabling...

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Detalles Bibliográficos
Autores principales: Medina, Exequiel, Villalobos, Pablo, Coñuecar, Ricardo, Ramírez-Sarmiento, César A., Babul, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443806/
https://www.ncbi.nlm.nih.gov/pubmed/30931977
http://dx.doi.org/10.1038/s41598-019-41819-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443806/
https://www.ncbi.nlm.nih.gov/pubmed/30931977
http://dx.doi.org/10.1038/s41598-019-41819-5

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