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The protonation state of an evolutionarily conserved histidine modulates domain swapping stability of FoxP1
Forkhead box P (FoxP) proteins are members of the versatile Fox transcription factors, which control the timing and expression of multiple genes for eukaryotic cell homeostasis. Compared to other Fox proteins, they can form domain-swapped dimers through their DNA-binding –forkhead– domains, enabling...
Autores principales: | Medina, Exequiel, Villalobos, Pablo, Coñuecar, Ricardo, Ramírez-Sarmiento, César A., Babul, Jorge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443806/ https://www.ncbi.nlm.nih.gov/pubmed/30931977 http://dx.doi.org/10.1038/s41598-019-41819-5 |
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