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Designing and Characterization of a Novel Delivery System for Improved Cellular Uptake by Brain Using Dendronised Apo-E-Derived Peptide

Neurodegenerative diseases (ND) are characterized by the progressive loss of neuronal structure or function mostly associated with neuronal death. The presence of the blood–brain barrier (BBB) is considered the main obstacle that prevents the penetration of almost all drugs rendering the diseases un...

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Detalles Bibliográficos
Autores principales: Al-azzawi, Shafq, Masheta, Dhafir, Guildford, Anna, Phillips, Gary, Santin, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443832/
https://www.ncbi.nlm.nih.gov/pubmed/30972332
http://dx.doi.org/10.3389/fbioe.2019.00049