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Analysis of the role of mutations in the KMT2D histone lysine methyltransferase in bladder cancer

Histone lysine methyltransferases (HMT) comprise a subclass of epigenetic regulators; dysregulation of these enzymes affects gene expression, which may lead to tumorigenesis. Here, we performed an integrated analysis of 50 HMTs in bladder cancer and found intrinsic links between copy number alterati...

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Detalles Bibliográficos
Autores principales: Ding, Beichen, Yan, Libin, Zhang, Yucong, Wang, Zhize, Zhang, Yangjun, Xia, Ding, Ye, Zhangqun, Xu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443872/
https://www.ncbi.nlm.nih.gov/pubmed/30984543
http://dx.doi.org/10.1002/2211-5463.12600