Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines

Fibroblast Growth Factor Receptors (FGFR1–4) have a critical role in the progression of several human cancers, including Squamous Non-Small-Cell Lung Cancer (SQCLC). Both non-selective and selective reversible FGFR inhibitors are under clinical investigation for the treatment of patients with tumors...

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Detalles Bibliográficos
Autores principales: Fumarola, Claudia, Bozza, Nicole, Castelli, Riccardo, Ferlenghi, Francesca, Marseglia, Giuseppe, Lodola, Alessio, Bonelli, Mara, La Monica, Silvia, Cretella, Daniele, Alfieri, Roberta, Minari, Roberta, Galetti, Maricla, Tiseo, Marcello, Ardizzoni, Andrea, Mor, Marco, Petronini, Pier Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443895/
https://www.ncbi.nlm.nih.gov/pubmed/30972293
http://dx.doi.org/10.3389/fonc.2019.00179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443895/
https://www.ncbi.nlm.nih.gov/pubmed/30972293
http://dx.doi.org/10.3389/fonc.2019.00179

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