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Negative Immunomodulatory Effects of Type 2 Porcine Reproductive and Respiratory Syndrome Virus-Induced Interleukin-1 Receptor Antagonist on Porcine Innate and Adaptive Immune Functions

Impaired innate and adaptive immune responses are evidenced throughout the course of PRRSV infection. We previously reported that interleukin-1 receptor antagonist (IL-1Ra) was involved in PRRSV-induced immunosuppression during an early phase of infection. However, the exact mechanism associated wit...

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Detalles Bibliográficos
Autores principales: Nedumpun, Teerawut, Techakriengkrai, Navapon, Thanawongnuwech, Roongroje, Suradhat, Sanipa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443931/
https://www.ncbi.nlm.nih.gov/pubmed/30972072
http://dx.doi.org/10.3389/fimmu.2019.00579