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Anti-nociceptive and Anti-inflammatory Activities of Asparacosin A Involve Selective Cyclooxygenase 2 and Inflammatory Cytokines Inhibition: An in-vitro, in-vivo, and in-silico Approach

Triterpenes possess anti-inflammatory and anti-nociceptive effects. In this study anti-inflammatory activities of Asparacosin A were evaluated' using in-vitro cyclooxygenases 1 and 2 (COX-1/2) inhibition assays. Moreover, anti-nociceptive activities were assessed in-vivo by carrageenan-induced...

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Detalles Bibliográficos
Autores principales: Karim, Nasiara, Khan, Inamullah, Khan, Waheed, Khan, Imran, Khan, Ajmal, Halim, Sobia Ahsan, Khan, Hizbullah, Hussain, Javid, Al-Harrasi, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443962/
https://www.ncbi.nlm.nih.gov/pubmed/30972073
http://dx.doi.org/10.3389/fimmu.2019.00581