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Valproic Acid Stimulates Hippocampal Neurogenesis via Activating the Wnt/β-Catenin Signaling Pathway in the APP/PS1/Nestin-GFP Triple Transgenic Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is an age-related neurodegenerative disease characterized by the deposition of amyloid-β (Aβ) peptides and neurofibrillary tangles (NFTs) and massive loss of neuronal cells in the brain. Adult hippocampus continuously generates new neurons throughout life to shape brain func...

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Detalles Bibliográficos
Autores principales: Zeng, Qinghua, Long, Zhimin, Feng, Min, Zhao, Yueyang, Luo, Shifang, Wang, Kejian, Wang, Yingxiong, Yang, Guang, He, Guiqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443965/
https://www.ncbi.nlm.nih.gov/pubmed/30971911
http://dx.doi.org/10.3389/fnagi.2019.00062