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Phosphorylated-Akt overexpression is associated with a higher risk of brain metastasis in patients with non-small cell lung cancer

Brain metastasis (BM) of non-small cell lung cancer (NSCLC) is relatively common and has a poor prognosis. Moreover, identifying which patients are more likely to develop BM is challenging. Akt, a serine/threonine-specific protein kinase, can be activated in various tumors, including lung cancer, an...

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Detalles Bibliográficos
Autores principales: Jin, Yu, Yuan, Ye, Yi, Minxiao, Han, Hu, Liu, Bo, Li, Qianxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444023/
https://www.ncbi.nlm.nih.gov/pubmed/30976664
http://dx.doi.org/10.1016/j.bbrep.2019.100625