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Protective Effects of Magnesium Glycyrrhizinate on Methotrexate-Induced Hepatotoxicity and Intestinal Toxicity May Be by Reducing COX-2

Magnesium isoglycyrrhizinate (MgIG), which has been widely employed to treat chronic hepatitis, is synthesized from 18-β glycyrrhizic acid, a main component of traditional Chinese medicine Glycyrrhiza uralensis Fisch. Although the protective effects of MgIG on methotrexate (MTX)-induced liver toxici...

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Detalles Bibliográficos
Autores principales: Cao, Yuzhu, Shi, Hang, Sun, Zhiguang, Wu, Jiawei, Xia, Yawen, Wang, Yufei, Wu, Yuanyuan, Li, Xiaoman, Chen, Wenxing, Wang, Aiyun, Lu, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444054/
https://www.ncbi.nlm.nih.gov/pubmed/30971913
http://dx.doi.org/10.3389/fphar.2019.00119