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Protective Effects of Magnesium Glycyrrhizinate on Methotrexate-Induced Hepatotoxicity and Intestinal Toxicity May Be by Reducing COX-2
Magnesium isoglycyrrhizinate (MgIG), which has been widely employed to treat chronic hepatitis, is synthesized from 18-β glycyrrhizic acid, a main component of traditional Chinese medicine Glycyrrhiza uralensis Fisch. Although the protective effects of MgIG on methotrexate (MTX)-induced liver toxici...
Autores principales: | Cao, Yuzhu, Shi, Hang, Sun, Zhiguang, Wu, Jiawei, Xia, Yawen, Wang, Yufei, Wu, Yuanyuan, Li, Xiaoman, Chen, Wenxing, Wang, Aiyun, Lu, Yin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444054/ https://www.ncbi.nlm.nih.gov/pubmed/30971913 http://dx.doi.org/10.3389/fphar.2019.00119 |
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