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OVA66 promotes tumour angiogenesis and progression through enhancing autocrine VEGF-VEGFR2 signalling

BACKGROUND: Activation of autocrine VEGF-VEGFR2 signalling in tumour cells activates cell proliferation, survival, and angiogenesis, all of which are crucial for tumour progression. Ovarian cancer-associated antigen 66 (OVA66) is now known to be overexpressed in multiple tumours and plays a role in...

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Detalles Bibliográficos
Autores principales: Song, Feifei, Chen, Qi, Rao, Wei, Zhang, Renfeng, Wang, Ying, Ge, Hailiang, Wei, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444131/
https://www.ncbi.nlm.nih.gov/pubmed/30833190
http://dx.doi.org/10.1016/j.ebiom.2019.02.051