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Chronic NO Restriction in Hypertensive Rats Increases Abdominal but Not Thoracic Aortic Intrinsic Stiffness via an Augmentation in Profibrotic Materials

The spontaneously hypertensive rat model with reduced NO synthesis (SHRLN) shares features with aging and hypertension in humans, among other a severe aortic stiffening. The present in vivo study aimed to compare thoracic (TA) and abdominal (AA) aortic stiffness in the SHRLN (treated 5 weeks with L-...

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Detalles Bibliográficos
Autores principales: Lindesay, George, Bézie, Yvonnick, Ragonnet, Christophe, Duchatelle, Véronique, Isabelle, Marc, Villeneuve, Nicole, Vayssettes-Courchay, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444237/
https://www.ncbi.nlm.nih.gov/pubmed/31016040
http://dx.doi.org/10.1155/2019/8070198