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Exosomes from Human Umbilical Cord Mesenchymal Stem Cells Reduce Damage from Oxidative Stress and the Epithelial-Mesenchymal Transition in Renal Epithelial Cells Exposed to Oxalate and Calcium Oxalate Monohydrate

OBJECTIVE: To investigate whether exosomes from human umbilical cord mesenchymal stem cells (hUC-MSCs) can protect against the toxic effects of oxalate and calcium oxalate monohydrate (COM) crystals in human proximal tubular epithelial (HK-2) cells. METHODS: Exosomes were isolated from hUC-MSCs, pur...

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Detalles Bibliográficos
Autores principales: Li, Dian, Zhang, Dan, Tang, Bo, Zhou, Yue, Guo, Wenhao, Kang, Qing, Wang, Zhang, Shen, Lianju, Wei, Guanghui, He, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444261/
https://www.ncbi.nlm.nih.gov/pubmed/31015841
http://dx.doi.org/10.1155/2019/6935806