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PPAR-γ Activation Exerts an Anti-inflammatory Effect by Suppressing the NLRP3 Inflammasome in Spinal Cord-Derived Neurons

Persistent inflammation disrupts functional recovery after spinal cord injury (SCI). Peroxisome proliferator-activated receptor gamma (PPAR-γ) activation promotes functional recovery in SCI rats by inhibiting inflammatory cascades and increasing neuronal survival. We sought to clarify the relationsh...

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Detalles Bibliográficos
Autores principales: Meng, Qing-Qi, Feng, Zhen-Cheng, Zhang, Xing-Liang, Hu, Li-Qiong, Wang, Min, Zhang, Hai-Feng, Li, Si-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444263/
https://www.ncbi.nlm.nih.gov/pubmed/31015796
http://dx.doi.org/10.1155/2019/6386729