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Combination of metformin and paclitaxel suppresses proliferation and induces apoptosis of human prostate cancer cells via oxidative stress and targeting the mitochondria-dependent pathway

Previous studies have reported that metformin (MET) has anticancer activity. In combination with chemotherapeutic drugs, MET reduces the dosage of chemotherapeutic drugs required and enhances anticancer efficacy. In the present study, the combination of MET and paclitaxel (PTX) in three human prosta...

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Detalles Bibliográficos
Autores principales: Zhao, Yuwan, Zeng, Xin, Tang, Huancheng, Ye, Dongcai, Liu, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444335/
https://www.ncbi.nlm.nih.gov/pubmed/30944622
http://dx.doi.org/10.3892/ol.2019.10119