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Combination of metformin and paclitaxel suppresses proliferation and induces apoptosis of human prostate cancer cells via oxidative stress and targeting the mitochondria-dependent pathway
Previous studies have reported that metformin (MET) has anticancer activity. In combination with chemotherapeutic drugs, MET reduces the dosage of chemotherapeutic drugs required and enhances anticancer efficacy. In the present study, the combination of MET and paclitaxel (PTX) in three human prosta...
Autores principales: | Zhao, Yuwan, Zeng, Xin, Tang, Huancheng, Ye, Dongcai, Liu, Jianjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444335/ https://www.ncbi.nlm.nih.gov/pubmed/30944622 http://dx.doi.org/10.3892/ol.2019.10119 |
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