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Fluorogenic D-amino acids enable real-time monitoring of peptidoglycan biosynthesis and high-throughput transpeptidation assays

Peptidoglycan (PG) is an essential cell wall component that maintains the morphology and viability of nearly all bacteria. Its biosynthesis requires periplasmic transpeptidation reactions which construct peptide cross-linkages between polysaccharide chains to endow mechanical strength. However, trac...

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Detalles Bibliográficos
Autores principales: Hsu, Yen-Pang, Hall, Edward, Booher, Garrett, Murphy, Brennan, Radkov, Atanas D., Yablonowski, Jacob, Mulcahey, Caitlyn, Alvarez, Laura, Cava, Felipe, Brun, Yves V., Kuru, Erkin, VanNieuwenhze, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444347/
https://www.ncbi.nlm.nih.gov/pubmed/30804500
http://dx.doi.org/10.1038/s41557-019-0217-x