Estradiol levels are elevated in older men with diffuse cutaneous SSc and are associated with decreased survival

BACKGROUND: Systemic sclerosis (SSc) is a female-predominant disease, characterized by excessive extracellular matrix deposition (ECM) with dermal and internal organ fibrosis. Considering the sex-based disparity in disease incidence, estradiol (E2), an estrogen form with pro-fibrotic effects, may pl...

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Detalles Bibliográficos
Autores principales: Baker Frost, DeAnna, Wolf, Bethany, Peoples, Christine, Fike, Jessica, Silver, Katherine, Laffoon, Maureen, Medsger, Thomas A., Feghali-Bostwick, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444502/
https://www.ncbi.nlm.nih.gov/pubmed/30940202
http://dx.doi.org/10.1186/s13075-019-1870-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444502/
https://www.ncbi.nlm.nih.gov/pubmed/30940202
http://dx.doi.org/10.1186/s13075-019-1870-6

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