FNDC5 attenuates obesity-induced cardiac hypertrophy by inactivating JAK2/STAT3-associated inflammation and oxidative stress

BACKGROUND: Chronic low-grade inflammation and oxidative stress play important roles in the development of obesity-induced cardiac hypertrophy. Here, we investigated the role of Fibronectin type III domain containing 5 (FNDC5) in cardiac inflammation and oxidative stress in obesity-induced cardiac h...

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Detalles Bibliográficos
Autores principales: Geng, Zhi, Fan, Wen-Yong, Zhou, Bing, Ye, Chao, Tong, Ying, Zhou, Ye-Bo, Xiong, Xiao-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444535/
https://www.ncbi.nlm.nih.gov/pubmed/30940158
http://dx.doi.org/10.1186/s12967-019-1857-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444535/
https://www.ncbi.nlm.nih.gov/pubmed/30940158
http://dx.doi.org/10.1186/s12967-019-1857-8

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