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Citrullination of HP1γ chromodomain affects association with chromatin

BACKGROUND: Stem cell differentiation involves major chromatin reorganisation, heterochromatin formation and genomic relocalisation of structural proteins, including heterochromatin protein 1 gamma (HP1γ). As the principal reader of the repressive histone marks H3K9me2/3, HP1 plays a key role in num...

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Detalles Bibliográficos
Autores principales: Wiese, Meike, Bannister, Andrew J., Basu, Srinjan, Boucher, Wayne, Wohlfahrt, Kai, Christophorou, Maria A., Nielsen, Michael L., Klenerman, David, Laue, Ernest D., Kouzarides, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444592/
https://www.ncbi.nlm.nih.gov/pubmed/30940194
http://dx.doi.org/10.1186/s13072-019-0265-x