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Polymorphisms in Pvkelch12 and gene amplification of Pvplasmepsin4 in Plasmodium vivax from Thailand, Lao PDR and Cambodia

BACKGROUND: Mutations in Pfkelch13 and Pfplasmepsin2/3 gene amplification are well-established markers for artemisinin and piperaquine resistance in Plasmodium falciparum, a widespread problem in the Greater Mekong Subregion (GMS). The Plasmodium vivax parasite population has experienced varying dru...

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Detalles Bibliográficos
Autores principales: Duanguppama, Jureeporn, Mathema, Vivek Bhakta, Tripura, Rupam, Day, Nicholas P. J., Maxay, Mayfong, Nguon, Chea, von Seidlein, Lorenz, Dhorda, Mehul, Peto, Thomas J., Nosten, Francois, White, Nicholas J., Dondorp, Arjen M., Imwong, Mallika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444602/
https://www.ncbi.nlm.nih.gov/pubmed/30940150
http://dx.doi.org/10.1186/s12936-019-2749-3