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Impact of LEDGIN treatment during virus production on residual HIV-1 transcription

BACKGROUND: Persistence of latent, replication-competent provirus is the main impediment towards the cure of HIV infection. One of the critical questions concerning HIV latency is the role of integration site selection in HIV expression. Inhibition of the interaction between HIV integrase and its ch...

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Detalles Bibliográficos
Autores principales: Vansant, Gerlinde, Vranckx, Lenard S., Zurnic, Irena, Van Looveren, Dominique, Van de Velde, Paulien, Nobles, Christopher, Gijsbers, Rik, Christ, Frauke, Debyser, Zeger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444612/
https://www.ncbi.nlm.nih.gov/pubmed/30940165
http://dx.doi.org/10.1186/s12977-019-0472-3