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Sequential disruption of ALV host receptor genes reveals no sharing of receptors between ALV subgroups A, B, and J

BACKGROUND: Previously, we showed that targeted disruption of viral receptor genes in avian leukosis virus (ALV) subgroups using clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9))-based genome editing confers resistance to ALV subgroups B and J. He...

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Detalles Bibliográficos
Autores principales: Lee, Hong Jo, Park, Kyung Je, Lee, Kyung Youn, Yao, Yongxiu, Nair, Venugopal, Han, Jae Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444617/
https://www.ncbi.nlm.nih.gov/pubmed/30976416
http://dx.doi.org/10.1186/s40104-019-0333-x