Two-stage estimation to adjust for treatment switching in randomised trials: a simulation study investigating the use of inverse probability weighting instead of re-censoring

BACKGROUND: Treatment switching is common in randomised trials of oncology treatments, with control group patients switching onto the experimental treatment during follow-up. This distorts an intention-to-treat comparison of the treatments under investigation. Two-stage estimation (TSE) can be used...

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Detalles Bibliográficos
Autores principales: Latimer, N. R., Abrams, K. R., Siebert, U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444622/
https://www.ncbi.nlm.nih.gov/pubmed/30935369
http://dx.doi.org/10.1186/s12874-019-0709-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444622/
https://www.ncbi.nlm.nih.gov/pubmed/30935369
http://dx.doi.org/10.1186/s12874-019-0709-9

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