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Stiffening of sickle cell trait red blood cells under simulated strenuous exercise conditions

The higher risk of vaso-occlusion events and sudden death for sickle-cell trait (SCT) athletes has been speculatively ascribed to SCT red blood cell (RBC) stiffening during strenuous exercise. However, the microenvironmental changes that could induce the stiffening of SCT RBCs are unknown. To addres...

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Detalles Bibliográficos
Autores principales: Xu, Zhensong, Zheng, Yi, Wang, Xian, Shehata, Nadine, Wang, Chen, Xie, Shaorong, Sun, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444709/
https://www.ncbi.nlm.nih.gov/pubmed/31057840
http://dx.doi.org/10.1038/micronano.2016.61