Exploiting biased reptation for continuous flow preparative DNA fractionation in a versatile microfluidic platform

A new approach is presented for preparative, continuous flow fractionation of sub-10-kbp DNA fragments, which exploits the variation in the field-dependent mobility of the DNA molecules based on their length. Orthogonally pulsed electric fields of significantly different magnitudes are applied to a...

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Detalles Bibliográficos
Autores principales: Gumuscu, Burcu, Bomer, Johan G., de Boer, Hans L., van den Berg, Albert, Eijkel, Jan C. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444976/
https://www.ncbi.nlm.nih.gov/pubmed/31057856
http://dx.doi.org/10.1038/micronano.2017.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444976/
https://www.ncbi.nlm.nih.gov/pubmed/31057856
http://dx.doi.org/10.1038/micronano.2017.1

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