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Exploiting biased reptation for continuous flow preparative DNA fractionation in a versatile microfluidic platform
A new approach is presented for preparative, continuous flow fractionation of sub-10-kbp DNA fragments, which exploits the variation in the field-dependent mobility of the DNA molecules based on their length. Orthogonally pulsed electric fields of significantly different magnitudes are applied to a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444976/ https://www.ncbi.nlm.nih.gov/pubmed/31057856 http://dx.doi.org/10.1038/micronano.2017.1 |