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Large-scale microfluidic gradient arrays reveal axon guidance behaviors in hippocampal neurons

High-throughput quantitative approaches to study axon growth behaviors have remained a challenge. We have developed a 1024-chamber microfluidic gradient generator array that enables large-scale investigations of axon guidance and growth dynamics from individual primary mammalian neurons, which are e...

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Detalles Bibliográficos
Autores principales: Bhattacharjee, Nirveek, Folch, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445017/
https://www.ncbi.nlm.nih.gov/pubmed/31057858
http://dx.doi.org/10.1038/micronano.2017.3