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Structural and biochemical evidence supporting poly ADP-ribosylation in the bacterium Deinococcus radiodurans

Poly-ADP-ribosylation, a post-translational modification involved in various cellular processes, is well characterized in eukaryotes but thought to be devoid in bacteria. Here, we solve crystal structures of ADP-ribose–bound poly(ADP-ribose)glycohydrolase from the radioresistant bacterium Deinococcu...

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Detalles Bibliográficos
Autores principales: Cho, Chao-Cheng, Chien, Chia-Yu, Chiu, Yi-Chih, Lin, Meng-Hsuan, Hsu, Chun-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445106/
https://www.ncbi.nlm.nih.gov/pubmed/30940816
http://dx.doi.org/10.1038/s41467-019-09153-6