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A generalized model for combining dependent SNP-level summary statistics and its extensions to statistics of other levels
Here I propose a fundamentally new flexible model to reveal the association between a trait and a set of genetic variants in a genomic region/gene. This model was developed for the situation when original individual-level phenotype and genotype data are not available, but the researcher possesses th...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445108/ https://www.ncbi.nlm.nih.gov/pubmed/30940856 http://dx.doi.org/10.1038/s41598-019-41827-5 |