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Novel avian paramyxovirus-based vaccine vectors expressing the Ebola virus glycoprotein elicit mucosal and humoral immune responses in guinea pigs

Paramyxovirus vaccine vectors based on human parainfluenza virus type 3 (HPIV-3) and Newcastle disease virus (NDV) have been previously evaluated against Ebola virus (EBOV) challenge. Although both the viral vectored vaccines efficiently induce protective immunity, some concerns remain to be solved....

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Detalles Bibliográficos
Autores principales: Yoshida, Asuka, Kim, Shin-Hee, Manoharan, Vinoth K., Varghese, Berin P., Paldurai, Anandan, Samal, Siba K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445115/
https://www.ncbi.nlm.nih.gov/pubmed/30940854
http://dx.doi.org/10.1038/s41598-019-42004-4