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Novel avian paramyxovirus-based vaccine vectors expressing the Ebola virus glycoprotein elicit mucosal and humoral immune responses in guinea pigs
Paramyxovirus vaccine vectors based on human parainfluenza virus type 3 (HPIV-3) and Newcastle disease virus (NDV) have been previously evaluated against Ebola virus (EBOV) challenge. Although both the viral vectored vaccines efficiently induce protective immunity, some concerns remain to be solved....
Autores principales: | Yoshida, Asuka, Kim, Shin-Hee, Manoharan, Vinoth K., Varghese, Berin P., Paldurai, Anandan, Samal, Siba K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445115/ https://www.ncbi.nlm.nih.gov/pubmed/30940854 http://dx.doi.org/10.1038/s41598-019-42004-4 |
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