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Oxidation destabilizes toxic amyloid beta peptide aggregation

The aggregation of insoluble amyloid beta (Aβ) peptides in the brain is known to trigger the onset of neurodegenerative diseases, such as Alzheimer’s disease. In spite of the massive number of investigations, the underlying mechanisms to destabilize the Aβ aggregates are still poorly understood. Som...

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Detalles Bibliográficos
Autores principales: Razzokov, J., Yusupov, M., Bogaerts, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445117/
https://www.ncbi.nlm.nih.gov/pubmed/30940901
http://dx.doi.org/10.1038/s41598-019-41931-6