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Lysine-specific demethylase 2A enhances binding of various nuclear factors to CpG-rich genomic DNAs by action of its CXXC-PHD domain

The lysine-specific demethylase 2A gene (KDM2A) is ubiquitously expressed and its transcripts consist of several alternatively spliced forms, including KDM2A and the shorter form N782 that lacks the 3′ end encoding F-box and LRR. KDM2A binds to numerous CpG-rich genomic loci and regulates various ce...

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Detalles Bibliográficos
Autores principales: Iuchi, Shiro, Paulo, Joao A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445129/
https://www.ncbi.nlm.nih.gov/pubmed/30940825
http://dx.doi.org/10.1038/s41598-019-41896-6