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Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors

The ubiquitin-proteasome system has been largely investigated for its key role in protein degradation mechanisms that regulate both apoptosis and cell division. Because of their antitumour activity, different classes of proteasome inhibitors have been identified to date. Some of these compounds are...

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Detalles Bibliográficos
Autores principales: Marastoni, Mauro, Trapella, Claudio, Scotti, Alessandra, Fantinati, Anna, Ferretti, Valeria, Marzola, Erika, Eleonora, Gallerani, Gavioli, Riccardo, Preti, Delia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445160/
https://www.ncbi.nlm.nih.gov/pubmed/28657369
http://dx.doi.org/10.1080/14756366.2017.1334649