Design, synthesis, and evaluation of novel 2-phenylpropionic acid derivatives as dual COX inhibitory-antibacterial agents

A series of 2-(4-substitutedmethylphenyl)propionic acid derivatives (6a–6m) were synthesized, characterized and evaluated for cyclooxygenase (COX) enzyme inhibitory and antimicrobial activity. Test compounds that exhibited good COX inhibition and antibacterial activity were further screened for thei...

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Detalles Bibliográficos
Autores principales: Karaca Gençer, Hülya, Acar Çevik, Ulviye, Kaya Çavuşoğlu, Betül, Sağlık, Begüm Nurpelin, Levent, Serkan, Atlı, Özlem, Ilgın, Sinem, Özkay, Yusuf, Kaplancıklı, Zafer Asım
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445163/
https://www.ncbi.nlm.nih.gov/pubmed/28413890
http://dx.doi.org/10.1080/14756366.2017.1310726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445163/
https://www.ncbi.nlm.nih.gov/pubmed/28413890
http://dx.doi.org/10.1080/14756366.2017.1310726

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