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Characterization of human S-adenosyl-homocysteine hydrolase in vitro and identification of its potential inhibitors

Human S-adenosyl-homocysteine hydrolase (SAHH, E.C.3.3.1.1) has been considered to be an attractive target for the design of medicines to treat human disease, because of its important role in regulating biological methylation reactions to catalyse the reversible hydrolysis of S-adenosylhomocysteine...

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Detalles Bibliográficos
Autores principales: Hao, Weiwei, Li, Yanhua, Shan, Qiuli, Han, Tian, Li, Wencheng, He, Sheng, Zhu, Kongkai, Li, Yumei, Tan, Xiaojun, Gu, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445193/
https://www.ncbi.nlm.nih.gov/pubmed/28933241
http://dx.doi.org/10.1080/14756366.2017.1370584