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Kinetic study on the inhibition of xanthine oxidase by acylated derivatives of flavonoids synthesised enzymatically

Studies have reported that flavonoids inhibit xanthine oxidase (XO) activity; however, poor solubility and stability in lipophilic media limit their bioavailability and applications. This study evaluated the kinetic parameters of XO inhibition and partition coefficients of flavonoid esters biosynthe...

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Detalles Bibliográficos
Autores principales: de Araújo, Maria Elisa Melo Branco, Franco, Yollanda Edwirges Moreira, Alberto, Thiago Grando, Messias, Marcia Cristina Fernandes, Leme, Camila Wielewski, Sawaya, Alexandra Christine Helena Frankland, Carvalho, Patricia de Oliveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445226/
https://www.ncbi.nlm.nih.gov/pubmed/28718686
http://dx.doi.org/10.1080/14756366.2017.1347165