Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action

Acridine orange (AO) a fluorescent cationic dye used for the management of human musculoskeletal sarcomas, due to its strong tumoricidal action and accumulation in the acidic environment typical of hypoxic tumors, was used for the preparation of a primary sulfonamide derivative. The rationale behind...

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Detalles Bibliográficos
Autores principales: Bragagni, Marco, Carta, Fabrizio, Osman, Sameh M., AlOthman, Zeid, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445237/
https://www.ncbi.nlm.nih.gov/pubmed/28335646
http://dx.doi.org/10.1080/14756366.2017.1302441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445237/
https://www.ncbi.nlm.nih.gov/pubmed/28335646
http://dx.doi.org/10.1080/14756366.2017.1302441

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