A strategy for early detection of response to chemotherapy drugs based on treatment-related changes in the metabolome

We describe a biomarker-based approach to delivering chemotherapy that entails monitoring treatment changes in the circulating metabolome that reflect efficacy. In-vitro, multiple tumor cell lines were exposed to numerous chemotherapeutics. Supernatants were collected at baseline and 72 hours post t...

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Detalles Bibliográficos
Autores principales: Amin, Shahil, Rattner, Jodi, Keramati, Mohammad Reza, Farshidfar, Farshad, McNamara, Mairéad G., Knox, Jennifer J., Kopciuk, Karen, Vogel, Hans J., Bathe, Oliver F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445409/
https://www.ncbi.nlm.nih.gov/pubmed/30939138
http://dx.doi.org/10.1371/journal.pone.0213942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445409/
https://www.ncbi.nlm.nih.gov/pubmed/30939138
http://dx.doi.org/10.1371/journal.pone.0213942

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