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A strategy for early detection of response to chemotherapy drugs based on treatment-related changes in the metabolome
We describe a biomarker-based approach to delivering chemotherapy that entails monitoring treatment changes in the circulating metabolome that reflect efficacy. In-vitro, multiple tumor cell lines were exposed to numerous chemotherapeutics. Supernatants were collected at baseline and 72 hours post t...
Autores principales: | Amin, Shahil, Rattner, Jodi, Keramati, Mohammad Reza, Farshidfar, Farshad, McNamara, Mairéad G., Knox, Jennifer J., Kopciuk, Karen, Vogel, Hans J., Bathe, Oliver F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445409/ https://www.ncbi.nlm.nih.gov/pubmed/30939138 http://dx.doi.org/10.1371/journal.pone.0213942 |
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