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Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection
CD8+ T cells play an important role in controlling of HIV and SIV infections. However, these cells are largely excluded from B cell follicles where HIV and SIV producing cells concentrate during chronic infection. It is not known, however, if antigen-specific CD8+ T cells are excluded gradually as p...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445460/ https://www.ncbi.nlm.nih.gov/pubmed/30897187 http://dx.doi.org/10.1371/journal.ppat.1007311 |