Cargando…

Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection

CD8+ T cells play an important role in controlling of HIV and SIV infections. However, these cells are largely excluded from B cell follicles where HIV and SIV producing cells concentrate during chronic infection. It is not known, however, if antigen-specific CD8+ T cells are excluded gradually as p...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Shengbin, Folkvord, Joy M., Kovacs, Katalin J., Wagstaff, Reece K., Mwakalundwa, Gwantwa, Rendahl, Aaron K., Rakasz, Eva G., Connick, Elizabeth, Skinner, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445460/
https://www.ncbi.nlm.nih.gov/pubmed/30897187
http://dx.doi.org/10.1371/journal.ppat.1007311