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The prevalence and antifolate drug resistance profiles of Plasmodium falciparum in study participants randomized to discontinue or continue cotrimoxazole prophylaxis

OBJECTIVE: Cotrimoxazole prevents opportunistic infections including falciparum malaria in HIV-infected individuals but there are concerns of cross-resistance to other antifolate drugs such as sulphadoxine-pyrimethamine (SP). In this study, we investigated the prevalence of antifolate-resistance mut...

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Detalles Bibliográficos
Autores principales: Juma, Dennis W., Muiruri, Peninah, Yuhas, Krista, John-Stewart, Grace, Ottichilo, Ronald, Waitumbi, John, Singa, Benson, Polyak, Christina, Kamau, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445470/
https://www.ncbi.nlm.nih.gov/pubmed/30897090
http://dx.doi.org/10.1371/journal.pntd.0007223