Helix–strand interaction regulates stability and aggregation of the human mitochondrial membrane protein channel VDAC3

Voltage-dependent anion channels (VDACs) are β-sheet–rich transmembrane β-barrels that are vital for metabolite transport across the mitochondrial membrane. Under cellular stress, human VDACs hetero-oligomerize and coaggregate with proteins that can form amyloidogenic and neurodegenerative deposits,...

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Detalles Bibliográficos
Autores principales: Gupta, Ankit, Mahalakshmi, Radhakrishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445588/
https://www.ncbi.nlm.nih.gov/pubmed/30674561
http://dx.doi.org/10.1085/jgp.201812272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445588/
https://www.ncbi.nlm.nih.gov/pubmed/30674561
http://dx.doi.org/10.1085/jgp.201812272

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