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Up-regulation of PCSK9 gene expression and diminished level of LDL-receptor in rat liver as a potential cause of post-lipectomy hypercholesterolemia

Studies designed to examine effects of fat mass reduction (including lipodystrophy and lipectomy) on human serum total and LDL-cholesterol concentrations are inconsistent. The purpose of this study was to examine effect of partial lipectomy in rats (as an experimental model of fat mass reduction in...

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Detalles Bibliográficos
Autores principales: Dettlaff-Pokora, Agnieszka, Sucajtys-Szulc, Elzbieta, Sledzinski, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445806/
https://www.ncbi.nlm.nih.gov/pubmed/30483910
http://dx.doi.org/10.1007/s11010-018-3484-8